Can Parasites Influence Drug Addiction?
- Jul 23
- 3 min read
Updated: Jul 30
1. Gut-Brain Axis Disruption
Parasites like Dientamoeba fragilis, Blastocystis hominis, and Toxoplasma gondii can interfere with the microbiome and vagus nerve signaling. This disruption affects the production of dopamine, serotonin, and GABA, key neurotransmitters that regulate mood, reward, and impulse control. An imbalance here can increase anxiety, impulsivity, and craving behavior, all hallmarks of addiction susceptibility.
2. Immune Dysregulation and Neuroinflammation
Chronic parasitic infections provoke persistent low grade inflammation. This inflammatory state, especially in the brain, has been associated with mood disorders, behavioral dysregulation, and even reward, seeking patterns that mirror substance dependence.
3. Toxoplasma gondii and Dopamine
