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Can Parasites Influence Drug Addiction?

  • Jul 23, 2025
  • 4 min read

Updated: Feb 2


1. Gut-Brain Axis Disruption

Parasites like Dientamoeba fragilis, Blastocystis hominis, and Toxoplasma gondii can interfere with the microbiome and vagus nerve signaling. This disruption affects the production of dopamine, serotonin, and GABA, key neurotransmitters that regulate mood, reward, and impulse control. An imbalance here can increase anxiety, impulsivity, and craving behavior, all hallmarks of addiction susceptibility.

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