

Parasites in Humans and Immune Terrain
By Maryjayne Aria, Author of Immune Health, Terrain and GcMAF
and Parasite Educational Specialist
Parasites in humans are often overlooked contributors to chronic illness, immune suppression, and systemic inflammation. Parasite burden may influence immune terrain, disrupt macrophage function, and contribute to long term inflammatory imbalance.
Immune terrain is the internal biological environment that determines immune resilience. It determines whether pathogens, parasites, and inflammatory processes are controlled or allowed to persist. Parasites, microbial imbalance, toxins, and chronic stress may all influence immune terrain.
Maryjayne Aria’s work focuses on the intersection between parasite burden, immune suppression, macrophage dysfunction, and chronic illness development and provides educational research focused on parasites in humans within the broader context of immune terrain science.

Immune terrain imbalance may involve:
-
Chronic inflammation
-
Reduced macrophage activation
-
Elevated Nagalase activity
-
Impaired immune surveillance
-
Persistent infections or parasite burden
Macrophages are central to immune regulation. They identify pathogens, parasites, abnormal cells, and coordinate immune response. When macrophage function becomes suppressed, immune terrain weakens.
Nagalase has been studied as a marker associated with immune dysfunction and macrophage activity. Research into GcMAF has explored its potential role in macrophage activation within specific research contexts.
Understanding immune terrain means examining:
-
Parasites in humans
-
Chronic inflammatory processes
-
Environmental toxic load
-
Microbial balance
-
Immune regulatory pathways
Parasite burden may contribute to immune exhaustion when the terrain remains compromised and can affect:
-
Digestive health
-
Nutrient absorption
-
Immune surveillance
-
Inflammatory signaling
-
Hormonal balance
-
Chronic fatigue and immune suppression
When immune terrain becomes compromised, macrophage activation may decline. Macrophages play a central role in identifying and clearing pathogens, parasites, and abnormal cells.
Chronic parasite burden may contribute to:
-
Persistent inflammation
-
Immune exhaustion
-
Nagalase elevation
-
Microbial imbalance
-
Long term chronic illness patterns
Education surrounding parasites must include immune function, inflammatory regulation, and terrain restoration. Treating parasites without addressing immune terrain may result in incomplete recovery. Maryjayne Aria integrates parasite education with immune terrain research to help individuals understand the broader biological context of chronic illness.
Learn More:

A Groundbreaking Book on Immunity and Terrain
I have poured more than two decades of research, clinical observation, and lived experience into my new book, Immune Health, Terrain and GcMAF. This is not just another health book. It is an invitation to understand the immune system in its full context, beyond symptoms, labels, and surface level answers.
In these pages, I explain why terrain matters, how macrophages truly work, and why GcMAF has been such a meaningful focus of my life’s work. I also speak honestly about what I have learned from families, practitioners, and patients who were searching not for miracles, but for clarity.
If you care about immune health, chronic conditions, or simply want to understand your body more deeply, this book was written for you. My hope is that it empowers you with knowledge, perspective, and confidence to ask better questions about your health.
The book is now available, and I would be honoured to have it in your hands. Those who purchase the downloadable edition (ebook) will be offered the A5 printed book for the cost of shipping only once it becomes available.
With deep appreciation, Maryjayne Aria.

Join "Parasite Queen" to gain insights into reclaiming your health from parasites. Find guidance on all available testing and treatment methods, deep dives into all common parasites affecting humans, common symptoms, supportive anti-parasitic diets, seeds, herbs. Explaining the pharmaceutical options including Ivermectin, Fenbendazole, Albendazole, and Mebendazole, with age-appropriate dosages.
Parasites are sadly a hidden factor in many health issues. Our health authorities “should” be advising us of the risks and providing treatments? In the absence of this care we are now experiencing rapidly rising cases of fatigue, sleep issues, emotional imbalance, skin issues, gut problems, IBS, infertility, mental health, immune imbalance, autism, ADHD, fibromyalgia and chronic diseases including cancer, parkinson’s, MS, lung disease, epilepsy, endometriosis, asthma, leukaemia and more. Addressing them can be a turning point in long-term healing.
